IGVP INSTITUTE • FLAGSHIP WORKBOOK

TECHNICALLY BRILLIANT.
COMMERCIALLY ARMED.

The Venture Framework for STEM

Strategies for Building & Scaling Tech Enterprises

“The hands-on, engineering-minded workbook built for the scientists, clinicians, and engineers ready to lead the next generation of healthcare innovation.”

6 ModulesVenture Literacy
FDA 510(k)SaMD & De Novo
Cap TableExcel Math Models
TRY LIVE SIMULATOR

From Lab to Ledger

— IGVP Operating Principle
The Venture Framework for STEM Hardcover Book
1st Edition • Hardcover & Digital PDF
340 Pages • Actionable ChecklistsISBN 978-1-989-102A

BUILT FOR THE PEOPLE BUILDING THE FUTURE OF HEALTHCARE

STEMCLINICALVENTUREREGULATORYCAPITALCOMMERCIALIZATION
INTERACTIVE WORKBOOK SAMPLE WIDGET

TRY THE WORKBOOK FRAMEWORKS LIVE

Test 3 of the real operational calculators and decision trees included inside the workbook right now.

Pre-Seed SAFE Dilution & Founder Retention Calculator

Adjust your target Pre-Seed SAFE raising amount and Valuation Cap to see founder equity retention after Series A conversion.

SAFE Capital Raised:$500,000 USD
Valuation Cap (Post-Money):$4,000,000 USD
DYNAMIC CAP TABLE OUTPUT
SAFE Dilution %:12.5%
Option Pool Reservation:10.0%
Defended Founder Equity:67.5%
Includes pre-built Excel formula templates with full SAFE to Series A conversion math inside Chapter 8.
THE STRUCTURAL GAP

SCIENCE CAN SOLVE THE PROBLEM.
BUT CAN YOU COMMERCIALIZE THE SOLUTION?

“STEM education trains you to solve complex technical problems, but leaves you blind to the commercial realities of the healthcare venture ecosystem.”

Existing business books stay surface-level, and generic startup platforms ignore healthcare-specific regulatory complexities.

01 • ACADEMIC FOUNDATION

WHAT STEM TEACHES

  • Deep Technical Research & Analysis
  • Rigorous Engineering & Lab Methodologies
  • Pure Scientific Knowledge Discovery
  • Clinical Physiology & Disease Pathology
  • Siloed Technical Problem Solving
THE VENTURE FRAMEWORK FOR STEM
02 • VENTURE EXECUTION

WHAT VENTURES REQUIRE

  • Healthcare Commercial Strategy & Go-To-Market
  • De-Risked FDA Regulatory Pathways (SaMD, 510k, De Novo)
  • CPT Reimbursement & Value-Based Care Models
  • Capitalization Table Modeling & Equity Defense
  • Institutional Investor Readiness & Diligence
STRUCTURED WORKBOOK CURRICULUM

6 MODULES OF TRUE VENTURE LITERACY

“Go beyond theory. This workbook gives you actionable checklists you can run this quarter and frameworks pulled from real venture capital operations.”

01COMMERCIAL BLIND SPOTS

Audit Commercial Blind Spots

Identify lethal commercial flaws before venture investors do. Learn how to map customer personas, clinical decision makers, and procurement friction points.

Chapters 1-3 • Checklists Included
02FDA / REGULATORY

De-Risk FDA Approvals

Navigate SaMD, 510(k), De Novo, and PCCP (Predetermined Change Control Plan) frameworks confidently without burning venture capital on avoidable delays.

Chapters 4-6 • Decision Trees
03ECONOMICS

Secure the Economics

Master commercial insurance reimbursement models, CPT/HCPCS code assignments, MAC coverage decisions, and value-based healthcare economics.

Chapters 7-9 • Audit Sheets
04CAPITALIZATION

Own Your Equity

Build, manipulate, and defend your capitalization table through Pre-Seed, SAFEs, Series A dilution, option pools, and investor anti-dilution provisions.

Chapters 10-12 • Excel Formulas
05CMS PLACEHOLDER

MODULE CONTENT

Coming Soon — Reserved for upcoming advanced clinical trial design & multi-site governance module.

IGVP CMS Editable Slot
06CMS PLACEHOLDER

MODULE CONTENT

Coming Soon — Reserved for institutional exit strategies, M&A diligence, and strategic buyer positioning.

IGVP CMS Editable Slot
TABLE OF CONTENTS

Explore Chapters & Framework Checklists

14 Detailed Chapters Across 6 Modules
Module 01

Chapter 1: Mapping the Healthcare Commercial Landscape

Understanding hospital purchasing committees, clinical decision-makers, and payor alignment.

Module 01

Chapter 2: Identifying Lethal Commercial Blind Spots

Module 02

Chapter 5: FDA Regulatory Compliance & Classification

Module 03

Chapter 8: Reimbursement Economics & CPT Coding

Module 04

Chapter 11: Capitalization Table Dilution & Equity Math

ACTUAL WORKBOOK SPREADS & TOOLS

NOT ANOTHER BUSINESS BOOK.

“A practical, no-nonsense workbook for turning advanced scientific capability into healthcare venture fluency.”

Workbook Page 42 - FDA Regulatory Decision Matrix
PREVIEW • PAGE 42
Expand Spread

FDA Regulatory De-Risking Matrix

Flowcharts for SaMD, 510(k) predicate identification, and De Novo submission prep.

CAP TABLE CALCULATORPREVIEW • PAGE 114
Founders Pool (Pre-SAFE)80.0% (8,000,000 sh)
Option Pool (Unallocated)10.0% (1,000,000 sh)
Institutional SAFE Conversion10.0% ($2.5M Post)
Post-Series A Target Retention54.2% Defended
Interactive Excel / Google Sheets formula templates included with book code.

Cap Table Dilution Defense Matrix

Pre-built equity models to simulate SAFE conversions and Series A anti-dilution.

REIMBURSEMENT CHECKLISTPREVIEW • PAGE 168
CPT Category I vs Category III Mapping
Medicare Administrative Contractor (MAC) LCD Audit
Commercial Payor Pilot Contract Requirements
Actionable clinical economics checklist ready to execute this quarter.

Healthcare Reimbursement Audit Sheet

Step-by-step audit for CPT coding, MAC coverage, and hospital value-based care.

TARGET AUDIENCE FLUENCY

BUILT FOR THE TECHNICALLY BRILLIANT.

01

STEM GRADUATE STUDENTS & POSTDOCS

Actively weighing an academic career against a venture path. Gain the commercial terminology and venture literacy required to evaluate technology licensing, spinouts, and founder equity.

Tailored Frameworks
02

CLINICIANS (MDs, RNs, PHARMACISTS, DENTISTS)

Translating front-line clinical insights into scalable ventures. Master FDA classification, hospital procurement workflows, and healthcare economics without leaving clinical practice behind.

Tailored Frameworks
03

EARLY-CAREER VC / PE ANALYSTS

Seeking technical and commercial fluency for deep-tech healthcare diligence. Use the workbook's audit frameworks to rapidly evaluate incoming pitch decks and scientific founder teams.

Tailored Frameworks
04

TECH-TRANSFER OFFICES (TTOs)

Looking for rigorous venture education frameworks to train faculty, postdocs, and researchers on de-risking patents and accelerating spinout deal velocity.

Tailored Frameworks
05

HEALTHCARE INCUBATORS & ACCELERATORS

Looking for a structured foundation for institutional venture education. Deploy the workbook as standard-issue curriculum across cohort onboarding.

Tailored Frameworks
THE HEALTHCARE VENTURE JOURNEY

FROM SCIENCE TO SCALE

A continuous, 6-stage operational pipeline for healthcare innovation leaders.

01

DISCOVER

Lab IP & Patent Strategy

02

VALIDATE

Clinical Needs Assessment

03

REGULATE

FDA Pathway & Clearance

04

COMMERCIALIZE

Payor Reimbursement & GTM

05

CAPITALIZE

Cap Table & Institutional VC

06

SCALE

Health System Adoption

“The Venture Framework for STEM is a practical, no-nonsense workbook that bridges the massive gap between advanced scientific capability and healthcare commercialization. Unlike generic startup advice, it provides engineering-minded professionals with the exact tools, cap tables, FDA regulatory pathways, and reimbursement frameworks needed to turn raw science into high-valuation healthcare ventures.”
FEATURED POSITIONING REVIEWSTEM PROFESSIONAL & HEALTHCARE VENTURE FELLOW
DEEPEN YOUR FLUENCY

READY TO GO BEYOND THE WORKBOOK?

“Turn venture literacy into hands-on experience through IGVP Institute courses, programs, and ecosystem opportunities.”

IGVP PUBLICATIONS LIBRARY

MORE FROM IGVP INSTITUTE

Dynamic CMS Editorial Grid
CURRENT TITLE

The Venture Framework for STEM

The foundational operating workbook for STEM professionals entering healthcare venture.

Active Page
CMS PLACEHOLDER
Future Publication Slot

Healthcare AI Venture Handbook

Upcoming title on SaMD AI algorithms, clinical validation, and HIPAA enterprise sales.

IGVP CMS Slot 02Coming Soon
CMS PLACEHOLDER
Future Publication Slot

The Clinical Translation Playbook

Upcoming title on multi-center trial design, IRB approvals, and hospital pilot contracts.

IGVP CMS Slot 03Coming Soon
LIVE ECOSYSTEM ENGAGEMENT

CONTINUE THE CONVERSATION

Dynamic / CMS-Ready Event Feed
OCTOBER 14, 2026GLOBAL WEBINAR

FDA SaMD & 510(k) De-Risking Masterclass

Live interactive breakdown of Module 02 regulatory decision trees with former FDA reviewers and IGVP venture fellows.

NOVEMBER 08, 2026FOUNDER WORKSHOP

Cap Table Math & SAFE Dilution Defense Clinic

Hands-on spreadsheet session modeling Pre-Seed to Series A dilution matrices from Module 04.

DECEMBER 02, 2026ANNUAL SUMMIT

IGVP Healthcare Commercialization Summit

Keynote ecosystem gathering bringing together STEM founders, clinicians, TTO directors, and deep-tech VCs.

STAY INFORMED

STAY CONNECTED TO THE VENTURE ECOSYSTEM

“Get updates on IGVP Institute courses, events, publications, and healthcare venture opportunities.”

TECHNICALLY BRILLIANT.
NOW GET COMMERCIALLY ARMED.

Start with the workbook. Continue with the ecosystem.